Studi etnofarmakologi tanaman obat suku zingiberaceae di Lereng Selatan Gunung Lawu, Jawa Timur
Abstract
Indonesia merupakan negara yang memiliki banyak keanekaragaman hayati yang tumbuh subur diberbagai daerah. Keanekaragaman ini mendorong berbagai pemanfaatan tanaman sebagai sarana pengobatan. Penelitian ini merupakan bentuk inventarisasi terhadap pemanfaatan tanaman obat sebagai sarana pengobatan yang dipercaya secara empiris. Metode : Menggunakan dua metode sampling, purposive sampling dan snowball sampling. Wawancara dilakukan menggunakan teknik semi terstruktur. Hasil : Tiga spesies dari famili zingiberace dipilih berdasarkan nilai FUV dan SUV tertinggi. Aktivitas farmakologi dari Curcuma longa L. sebagai antijamu adalah senyawa kimia ar-turmerone yang mampu menurunkan aktivitas membran jamur dan senyawa kimia diferuloylmethane yang berkerja sebagai angen antinyeri dengan menekan pembentukan agen COX. 6-ginggerol dari spesies Zingiber officinale Rosce diketahui bekerja sebagai agen antiinflamasi dengan mengontrol sitokin sehingga peradangan menurun. Terakhir Kaempferia galanga L. dengan senyawa kimia Ethyl p-methoxycinnamate dengan menekan sitokin menghambat angiogenesis dengan menghambat fungsi endotel sehingga peradangan dapat ditekan.
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